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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUP107
All Species:
19.7
Human Site:
S224
Identified Species:
36.11
UniProt:
P57740
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57740
NP_065134.1
925
106374
S224
V
T
W
R
L
L
A
S
L
Y
R
D
R
I
Q
Chimpanzee
Pan troglodytes
XP_522462
925
106407
S224
V
T
W
R
L
L
A
S
L
Y
R
D
R
I
Q
Rhesus Macaque
Macaca mulatta
XP_001117201
925
106577
S224
V
T
W
R
L
L
A
S
L
Y
R
D
R
I
Q
Dog
Lupus familis
XP_531670
686
80198
S56
Q
K
F
S
K
T
A
S
M
L
W
L
L
Q
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH74
926
106699
S225
V
T
W
R
L
L
A
S
L
Y
R
D
R
I
Q
Rat
Rattus norvegicus
P52590
926
107190
A224
M
V
T
W
R
L
L
A
S
L
Y
R
D
R
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511475
975
112083
S274
V
T
W
R
L
L
A
S
L
Y
R
D
R
I
Q
Chicken
Gallus gallus
XP_416082
885
102049
L224
N
L
F
Q
K
D
A
L
V
R
Q
S
Q
L
V
Frog
Xenopus laevis
NP_001091312
916
105253
E228
R
I
Q
S
A
L
E
E
E
N
M
F
E
I
A
Zebra Danio
Brachydanio rerio
NP_001025338
919
105378
V224
T
S
L
Y
R
D
R
V
Q
T
V
L
E
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609446
845
97363
F215
M
A
W
E
N
T
L
F
Q
L
E
N
L
Q
G
Honey Bee
Apis mellifera
XP_397116
878
102262
E224
P
M
E
D
D
L
E
E
S
N
T
Y
I
S
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791160
1004
115439
D300
L
I
G
S
L
Y
Q
D
R
Q
M
S
A
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
98.4
70.8
N.A.
91.2
91.5
N.A.
82.8
78.1
74.8
67.3
N.A.
32
33.1
N.A.
43.9
Protein Similarity:
100
99.3
99.3
72.2
N.A.
95.5
95
N.A.
89
86.5
86.3
81.8
N.A.
50.8
53.7
N.A.
61.9
P-Site Identity:
100
100
100
20
N.A.
100
6.6
N.A.
100
6.6
13.3
0
N.A.
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
33.3
N.A.
100
20
N.A.
100
46.6
13.3
6.6
N.A.
20
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
54
8
0
0
0
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
8
16
0
8
0
0
0
39
8
0
16
% D
% Glu:
0
0
8
8
0
0
16
16
8
0
8
0
16
16
8
% E
% Phe:
0
0
16
0
0
0
0
8
0
0
0
8
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
16
0
0
0
0
0
0
0
0
0
0
8
47
8
% I
% Lys:
0
8
0
0
16
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
8
8
0
47
62
16
8
39
24
0
16
16
8
0
% L
% Met:
16
8
0
0
0
0
0
0
8
0
16
0
0
0
0
% M
% Asn:
8
0
0
0
8
0
0
0
0
16
0
8
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
8
8
0
0
8
0
16
8
8
0
8
16
47
% Q
% Arg:
8
0
0
39
16
0
8
0
8
8
39
8
39
8
0
% R
% Ser:
0
8
0
24
0
0
0
47
16
0
0
16
0
8
0
% S
% Thr:
8
39
8
0
0
16
0
0
0
8
8
0
0
0
0
% T
% Val:
39
8
0
0
0
0
0
8
8
0
8
0
0
0
8
% V
% Trp:
0
0
47
8
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
8
0
8
0
0
0
39
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _